Selective Impairment of Central Mediation of Baroreflex in Anesthetized Young-Adult Fischer 344 Rats Following Chronic Intermittent Hypoxia
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چکیده
Selective Impairment of Central Mediation of Baroreflex in Anesthetized Young-Adult Fischer 344 Rats Following Chronic Intermittent Hypoxia He Gu, Min Lin, Jianyu Liu, David Gozal, Karie E Scrogin, Robert Wurster, Mark W Chapleau, Xiuying Ma, Zixi (Jack) Cheng* Biomolecular Science Center, Burnett College of Biomedical Sciences, University of Central Florida, Orlando, FL 32816, Kosair Children’s Hospital Research Institute, Department of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky 40202, Department of Pharmacology and Physiology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL 60153, Department of Internal Medicine, University of Iowa, and Veterans Affairs Medical Center, Iowa City, IA 52242, Running Header: CIH Modified Baroreflex Circuitry in Anesthetized Rats
منابع مشابه
Selective impairment of central mediation of baroreflex in anesthetized young adult Fischer 344 rats after chronic intermittent hypoxia.
Baroreflex control of heart rate (HR) is impaired after chronic intermittent hypoxia (CIH). However, the location and nature of this response remain unclear. We examined baroreceptor afferent, vagal efferent, and central components of the baroreflex circuitry. Fischer 344 (F344) rats were exposed to room air (RA) or CIH for 35-50 days and were then anesthetized with isoflurane, ventilated, and ...
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